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To further confirm the interaction of butyrate and the rise in GLP-1 levels, we used the human L-cell line NCI-H716 and measured its GLP-1 secretion and synthesis capacity

In clinical trials, many people lost a meaningful share of their body weight over about a year when medication was combined with lifestyle changes

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While these results will be disappointing for people living with dementia, the company reported that treatment did improve Alzheimers-related biomarkers leaving open a tiny window of hope that in future this drug might be effective if used earlier as a preventative strategy